BDBM466577 2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6′-dihydro[2,4′-bipyridin]-1′ (2′H)-yl]ethyl}propanamide::US10800755, Example 31::US11014905, Example 31

SMILES CC(C)(C)C(=O)NCCN1CCC(=CC1)c1cccc(n1)C(F)(F)F

InChI Key InChIKey=MLIIQBGETYKWJT-UHFFFAOYSA-N

Data  3 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 466577   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataKi:  1.28E+3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataIC50:  0.300nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466577(2,2-Dimethyl-N-{2-[6-(trifluoromethyl)-3′,6&...)
Affinity DataEC50:  35nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent